报告题目： Rational molecular design for sustainable energy

报告人：黄美兰(英国贝尔法斯特女王大学）

邀请人：刘迎春

时间：2017年3月23日下午2：00

地点：教8－500

报告人简介：

Dr Meilan Huang is a principle investigator at School of Chemistry and Chemical Engineering at Queen’s University Belfast since 2007. She has extensive experience in developing and applying computational chemistry/biology in rational protein engineering and rational drug design. Another area of her group is rational design of functional materials for perovskite solar cells. She has been leading several interdisciplinary research projects using computational modeling to guide experimental design. She has over 30 publications on high-impact peer-reviewed journals such as ACS Catalysis and J Phys Chem. She is the academic leader of an interdisciplinary biotechnological project (￡763,210) on development of computational and molecular biology platforms for industry and QUB. She received her PhD degree in Physical Chemistry from Zhejiang University in 2003. Prior to her faculty position at QUB, she was a postdoctoral fellow in University of Calgary in 2003, a Welcome trust research fellow at the University of Oxford from 2004 to 2006 and a research fellow at University of British Columbia in 2006.

Recent publications:

1. D.F.A.R. Dourado, S Pohle, A T.P. Carvalho, D S.Dheeman, J M. Caswell, R Brown, D J. Quinn, CAllen, L Kulakov, M Huang. Rational design of a (S)-selective transaminase for asymmetric synthesis of (1S)-1-(1,1'-biphenyl-2-yl)ethanamine. ACS Catalysis.2016, 6, 7749�7759.

2. M Huang, K Wei, X Li, J McClory, G Hu, JW Zou, D.J.Timson. QM/MM study on phosphorylation mechanism of phosphomevalonate kinase: Implication for high-specificity production of isoprenol as next generation of biofuel.J. Phys. Chem. B,2016, 120, 10714�10722.